2022 WI Epigenetics Group Symposium

2022 WI Epigenetics Group Symposium

October 13, 2022 | 9am-6pm

Union South and Discovery Building

Agenda:  Union South, Varsity Hall III

TIME

ACTIVITY

SPEAKER

8:30-8:55

Sign in – Light Refreshments

9:00-9:10

Welcome and Opening Remarks

Dr. John Denu

9:10-10:10

Keynote Address:
The function and inhibition of histone “reader” domains found within chromatin remodeling complexes

Dr. Emily Dykhuizen

10:10-10:30

Coffee Break

Session 1

Co-Chairs: Andrew Tak & Lily Miller

10:30-10:55

Transgenerational epigenetic inheritance in mammals: how strong is the evidence?

Dr. Hasan Khatib

11:00-11:25

The Battle of the Sexes: Epigenetic Marks Ensure Ovary vs Testis Differentiation

Dr. Joan Jorgensen

11:30-11:45

Lightning Talks Set 1 – Students

Tyler Gibson
Nguyet Minh Hoang
Caleb Dillingham

11:45-1:00

Lunch Break

Session 2

Co-Chairs: Clairine Larsen & Cassie Leech

1:00-1:25

A Systems Approach Reveals EZH2 as a Bulwark Against Neuroinflammation in Epilepsy

Dr. Avtar Roopra

1:30-1:55

Ovarian cancer super-enhancers: Druggable targets and platinum-based chemotherapy interactions

Dr. Jessica Lang

2:00-2:15

Lightning Talks Set 2 – Students

Alberca Doto
Zena Jensvold
Ahmed Ali

2:15-2:30

Coffee Break

2:30-2:55

How do viral pathogens manipulate the epigenome to establish infection?

Dr. Kinjal Majumder

3:00-3:25

WARF Therapeutics and targeting epigenetic mechanisms

Dr. Jonathan

Young

3:30

Closing Remarks

Dr. Rupa Sridharan

Poster Session 3:30-5pm, Discovery Building, 2nd Floor West

Poster Guide: Discovery Building, 2nd Floor West

POSTER TITLE

PRESENTER

1

BAP1 deubiquitination in Polycomb regulation of myelin homeostasis

John Svaren

2

Cisplatin sensitivity in ovarian cancer cell lines of various histotypes

Kristin Adams

3

Identifying gene regulatory networks driving cell fate

Khagani Eynullazada

4

Silencing transposable elements: functions and interactions of the Human Silencing Hub (HuSH) Complexes

Zena Jensvold

5

Synergy of cisplatin with epigenetic inhibitors targeting super-enhancers in cisplatin-resistant high-grade serous ovarian carcinoma

Jae-Rim Wendt

6

Defining properties regulating pioneer-factor binding and function

Tyler Gibson

7

DNMT3A-Mediated Oxidative Phosphorylation and Ibrutinib Resistance in Mantle Cell Lymphoma

Nguyet Minh Hoang

8

Elucidating the Role of EZHIP in Tumor Development

Truman Do

9

The Influence of MHC Class I and II on T Cell Responses in Mouse Melanoma Tumors

Amy Erbe-Gurel

10

Posttranscriptional control of pluripotency by histone demethylases

Caleb Dillingham

11

Spatial and Epigenetic Regulation of AAV2 Latency

Rhiannon Abrahams

12

Regeneration and Developmental Enhancers Are Differentially Compatible with Minimal Promoters

Ian Begeman

13

Epigenetic regulation of recombinant AAV gene therapy vectors

Clairine Larsen

14

Kinetics and Molecular Regulation of Nucleosomal Deacetylation by NAD+ Dependent Deacetylase SIRT6

Jose Moran

15

Dietary protein restriction mitigates the development and progression of Alzheimer’s disease

Reji Babygirija

16

dCypher®: A High-Throughput Method for the Assessment of Chromatin Interacting Proteins

Laiba Kahn,Scott Hammers, Hailey Taylor, Saarang Gopinath

17

Restriction of branched-chain amino acids and methionine have different effects on metabolic health in diet-induced obese mice

Mariah Callubag

18

Blood DNA Methylation Patterns in Established Alzheimer’s Disease Genes Based on Disease Status or APOE ε4 genotype

Phillip Bergmann

19

Screening of histone post-translational modifications in castration resistant prostate cancer reveals CHD1 gene deficiency engenders a distinct epigenetic profile

Tanaya Purohit

20

Characterizing the functional role of DNA methylation in the long-range regulation of gene expression in neurodevelopmental disorders

Alberca Doto

21

Transgenerational inheritance of a folate-driven axon regeneration trait is mediated by sperm DNA methylation

Andy Madrid

22

Rta is the principal activator of Epstein-Barr virus epithelial lytic transcription.

Ahmed Ali

23

The CTRL2 insulator of HSV-1 limits heterochromatinization of immediate early genes during the initiation of productive lytic infection

Ziyun Ye

24

Understanding the role of Bromodomain Extra-Terminal (BET) protein BRD4 in integrated Human Papilloma Virus (HPV) associated Head and Neck Squamous Cell Carcinoma (HNSCC).

Dhruthi Suresh

25

Decoding the Epigenetic Language of Gut Microbiome

Jessica Han

26

EZH2 tempers activation of pro-epileptic JAK/STAT signaling to mitigate disease progression.

Olivia Hoffman